Smoking is the biggest risk factor for non-AIDS-defining cancers in people living with HIV

Theo Smart
Original Article: 

Smoking appears to contribute most to the burden of non-AIDS-defining cancers diagnosed in people living with HIV in the US, out of all the potential modifiable risk factors – including hepatitis B or C, low CD4 cell count, an AIDS diagnosis or having an unsuppressed viral load – according to a study reported last week at the Conference on Retroviruses and Opportunistic Infections (CROI 2015) in Seattle, USA.

The study, presented by Keri Althoff of Johns Hopkins Bloomberg School of Public Health, found that the population attributable fraction (PAF) – or the proportion of non-AIDS cancer cases that could be avoided by people with HIV if they had the same level of smoking as the reference population – was 37% for all non-AIDS cancers and 29% if lung cancer was excluded.

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