Expanded PrEP use in San Francisco could reduce infection rate

Original Article:  bit.ly/1E77lBk

SEATTLE — A model predicting HIV transmission in San Francisco with expanded use of pre-exposure prophylaxis suggests that the number of new infections could decrease by 50% throughout the city, according to data presented at CROI 2015.

“San Francisco is an early adopter and sentinel of HIV prevention strategies, including routine HIV testing, nucleic acid testing, early HIV treatment and grassroots initiatives such as seroadaptive sexual practices,” Robert M. Grant, MD, MPH, Betty Jean and Hiro Ogawa Endowed Investigator with the Gladstone Institutes in San Francisco, said during his presentation. “PrEP use started to rise in San Francisco in 2013, but goals for PrEP scale-up have not yet been established.”

Robert M. Grant?

Data from surveys of sexual practices and PrEP use among men who have sex with men indicated that 16,089 HIV-negative individuals are at substantial risk for HIV and are eligible for PrEP, Grant said. However, only 5,059 of those reported PrEP use in the past year, meaning only 31% of eligible people were using PrEP. Using data from the iPrEx Open Label Extension (OLE) trial in San Francisco, Grand and colleagues calculated the potential impact of PrEP scale-up.

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